Clindamycin: Uses, Dosage, Benefits and Side Effects of the Antibiotic

Clindamycin Phosphate : Clindamycin is an antibiotic medication which is normally available as a pill that can be swallowed or as a cream to be applied in the affected area. It normally works by stopping further growth of the bacteria.

What is Clindamycin Used for?

Clindamycin is an antibiotic that is used to treat a number of bacterial infections in the body. Some of these infections include, ear infections, bone and joint infections, dental infections, pneumonia, strep throat and endocarditis among others. It is also used to treat acne and can be used as an addition to quinine which is used to cure malaria.

Clindamycin Dosage

This dosage usually varies in individuals as it is dependent on a number of factors such as age, the bacterial infection being treated, the severity of the condition being treated, other medical conditions one might be having and how one reacts to the first dose.  In children, the dosage is prescribed according to their weight while in adults it is based on their medical conditions and their response to the treatment.

This drug is usually available in to forms. One is the generic form, Clindamycin which is an oral capsule and is available in 75 mg 150 mg and 300 mg. the other form is the brand, Cleocin which is also available as an oral capsule and is available in 75 mg, 150 mg and 300 mg.

In adults, those who are 18 years and older, the serious infections are usually treated with the 150 mg or the 300 mg, a dose which has to be taken after every  hours. The most severe infections are normally treated with the 300 mg to 40 mg which is supposed to be taken after every 6 hours.

In children, those aged 0 to 17 years, the serious infections are treated with 8 mg to 16 mg/kg of body weight per day and is taken in 3-4 hours equally divided doses, for the severe infections, they are treated with 16 to 20 mg/kg of body weight per day taken in 3-4 equally divided doses.

This medication is normally orally with or without food usually at least 4 times a day or as directed by your health care professional. It should be taken with a glass of water unless instructed otherwise. It is advisable for anyone using the drug not to lie down for about 10 minutes of taking the drug. For best results, patients are normally advised to take their prescription at evenly spaced times probably at the same time every day.

What is Clindamycin 300 mg Used for?

Clindamycin 300 mg is an oral medication that is used to inhibit the growth of a wide variety of bacterial infections in human beings and as such it would not work for virus infections. It is also used to treat several other conditions that may not necessarily be listed on the drug prescription uses such as for dental procedures and used in patients with certain heart conditions such as the artificial heart valves to help prevent serious infections but only when prescribed by your health care professional.

What are The Side Effects of Clindamycin HCL

Most medical drugs come along with various side effects some are mild and common while others might be serious side effects. The case is the same with the use of Clindamycin HCL drug. Patients who have interacted with this drug have reported some various side effects some of which are common and some are unique to certain users.

Some of the less serious side effects of this drug include;

  1. Development of allergic reactions such as hives, swelling of the face, tongue, throat and lips
  2. Difficulty in breathing
  3. Change in bowel habits
  4. Pain in the joints
  5. Mild nausea, stomach pain or vomiting
  6. Vaginal itching or discharge

Some of the serious side effects that patients have experienced when using the drug include;

  1. Jaundice; a condition that causes the yellowing of the skin and eyes.
  2. Diarrhea that is watery and bloody
  3. Fever and chills
  4. Body aches
  5. Flu symptoms
  6. Sores in the mouth and throat
  7. Unusual bleeding especially in the mouth, nose, vagina or rectum.
  8. Severe skin reaction such as sore throat, burning in your eyes, skin pain that usually leads to the development of red or purple skin rash, swelling in the face or tongue

This is just but a list of the common side effects that patients have reported to have experienced. One may or may not experience these side effects since all patients are different and their interaction with certain drugs might differ.

It is however important to note that if you experience any of these symptoms or other side effects, you should immediately contact your health care provider so that they can change your prescription or take the appropriate next move.

Prolonged or repeated use of this drug has however been noted to cause oral thrush which manifests itself as patches on your mouth and vaginal infection which results in a change in vaginal discharge. Also, the prolonged use of this drug will usually cause the drugs to no longer be effective in curing bacterial infections.


Before you start taking this medication it is important to tell your health care provider your medical history especially if you have any kidney diseases, liver diseases, allergic reactions and stomach or intestinal diseases. Also let them know if you are taking any medications at the moment, this is because certain drug interaction may change the way your medication s work and may even result to adverse side effects.

Some of the drugs that might interact with these drugs include macrolide antibiotics and kaolin-pectin. Birth controls such as pills, the ring or patch can reduce the effectiveness of the drug and may cause the birth controls to fail.

This is mainly because the Clindamycin drug usually causes live bacterial vaccines not to work well hence it is also advisable for one not to take any immunizations or vaccinations while under this drug medication.

Situations in which you need to inform your health provider

  1. If you are undergoing surgery and have been under this drug
  2. If you are pregnant or breastfeeding.

Clindamycin and Acne

Antibiotics are commonly used to treat acne because they are known to decrease the number of bacteria in and around skin. They also work by reducing the irritating chemicals produced by the white blood cells and also by reducing the concentration of fatty acids in the sebum which results in reduction of the inflammatory response.

Acne is caused by the hair follicles in the skin blocking leading to an overgrowth of normal skin bacteria which destroys the lining of the follicle hence the follicular material enters the dermis causing an inflammatory response commonly known as Acne.

There are several types of antibiotics that are used to treat acne some of which include tetracycline, erythromycin, minocin, doxycycline and Clindamycin, which is now our area of interest. It is however important to note that some antibiotics work best for certain types of acne hence it is important to visit a dermatologist so as to be able to determine which will work best for you.

Clindamycin is a useful oral antibiotic used to treat acne and is mostly prescribes as a topical antibiotic. The dosage is normally 75 mg to 150 mg which is to be taken twice a day. The major side effect that comes with using Clindamycin to treat acne is that it causes a serious intestinal infection caused by bacteria. Topical Clindamycin is available as Cleocin-T, Clinda-Derm, Clingagel, Clindets and Evoclin.

A common side effect of using this drug by women is causing vaginal yeast infection and can also lessen the effectiveness of birth control pills and prolonged use of the drug often leads to resistance.

Clindamycin Phosphate

Clindamycin Phosphate is a phosphate salt form of Clindamycin. It is made by the modification of lincomycin. Clindamycin Phosphate is used in topical preparations.

What is Clindamycin Phosphate Used for?

This is a topical antibiotic that is available in generic for and is used to treat acne vulgaris which is a skin condition. Some of the common side effects of using the Clindamycin phosphate include;

  • Dry skin
  • Skin redness
  • Oily skin
  • Stomach upset
  • Burning and itchiness of the skin
  • Peeling of the skin
  • Abdominal pain

Clindamycin Phosphate Gel

Clindamycin is generally an antibiotic that is used to treat bacterial infection by inhibiting the growth of bacteria. Clindamycin gel is used to treat acne by reducing the number of acne lesions.

How to use Clindamycin Phosphate gel

Clindamycin phosphate is a medication to be used only on the skin. So as to use this medication, you first need to clean and dry the affected are then apply the medicine as per the instructions or as advised by your health care provider.

If you are using the lotion form of the medicine, shake the bottle well before use and then apply a thin layer of the lotion on the clean and dry affected area. Use this as prescribed by the doctor.

If using the foam form of the medicine, use enough to just cover the affected area. Avoid spraying it directly on your hands as this will cause it to melt when it comes into contact with warm hands.

If using the medicated swab or pad, apply a good amount on the affected area and gently smear it with the swab or pad which should be immediately discarded after use.

Make sure you wash your hands after being in contact with the medicine. Avoid contact with mouth, eyes, nose or any area with a broke skin. In case of an accidental contact with these areas, make sure you rinse well with plenty of cool water.

It normally takes anywhere between 2 to 6 weeks to notice any improvements in the affected skin condition.

Adapalene Gel

The Adapalene gel is used to treat acne by decreasing the number and severity of the acne pimples. It also promotes quick healing of acne pimples that develop. This gel belongs to the retinoid class of medications. It is known to decrease the growth of cells, decreasing swelling and inflammation.

Adapalene and Clindamycin Phosphate Gel

The combination of Adapalene and Clindamycin Phosphate provides for a better, safer and more efficient treatment of acne as proved by a research conducted by the World Congress of Dermatology. Patient who used this drug combination could see the effects as soon as two weeks.

Clindamycin Phosphate Topical Gel

The Clindamycin phosphate tropical gel is an antibiotic that belongs to the group of antibiotic known as lincosamides.

What is It Used for?

Clindamycin phosphate topical gel is an antibiotic that is used to treat acne vulgaris. Acne vulgaris is a common form of acne that consists of non-inflammatory and mildly inflammatory lesions.

Some of the common side effects of using Clindamycin phosphate topical gel include;

  • Itching and peeling of the skin
  • Diarrhea that is bloody
  • Intestinal condition called colitis.
  • Abdominal pain
  • Gastrointestinal disturbance
  • Bacterial infection
  • Inflammation of hair follicles.


Before using this drug, patients are advised to inform their health care providers in case they are allergic to the medication or if they have any other allergies since the product may contain inactive ingredients that cause allergic reactions.

Patients who have medical history especially of chronic asthma, hay fever, enteritis and intestinal diseases should also inform their health care providers. Pregnant women should also tell their doctor in case they are to be administered with this medicine.

Patients who are under medication of another drug should also make it known since the drug interaction may affect the effectiveness of the drugs. The interaction could also lead to serious side effects hence this is a necessary precaution.

How Effective is Clindamycin Phosphate in Curing Acne

Clindamycin phosphate is a very effective medication used to treat severe cases of acne as for this reason, this drug is usually not for sale over the counter; it must be prescribed by the doctor. It works by decreasing the amount of fatty acids that cause the skin inflammations.

This medicine is also known as Cleocin T. is effective but patients should be aware of its possible side effects. It is most preferred over the oral medication since its effects are less severe than those of the oral medication.

Patients who use the Cleocin T. medication as prescribed usually start to notice the improvements starting from two weeks. Patients are advised to continue using the medication even after the acne clears until their doctor tells them to stop. Stopping the medication as soon as you notice the improvements is risky as the medicine might not have cleared the acne completely. This will lead to the bacteria causing the acne becoming resistant to this type of medications hence it will be more difficult to treat the acne in the future.

Clindamycin Phosphate Topical Gel and Pregnancy

It is estimated that in every pregnancy, a woman has a 3% to 5% probability of giving birth to a baby with a birth defect, which is commonly referred to as her background risk. The use of Clindamycin phosphate topical gel will be evaluated to see whether it has any effect on the birth of her child.

Clindamycin phosphate is an antibiotic that is known to treat and prevent bacterial infection and also to treat acne. One side effect of using this medication is that it can cause an inflammation of the colon due to overgrowth of a certain bacteria.

In Pregnancy, the use of the medication does not seem to increase the chances of developing an inflammation of the colon.

Some studies have shown that the use of this gel does not increase the chance of giving birth to baby with a defect. A further study that was conducted on pregnant women in their 2nd and 3rd trimester who were treated of their vaginosis with Clindamycin Phosphate did not show any risk of using the medication. Matter of fact, it helped lower their chances of having a late miscarriage and a pre-term birth.

If the medication is being used on the face, there is only a small amount of the medicine that is absorbed into the body hence the pregnancy will only be exposed to a little or no amount of the medication hence the chances of resulting into a complication are minimal.

However, it is important for patients to remember that each and every individual is different and hence what applies to one may not to another. It is therefore highly recommended that if you are pregnant, you should seek the advice of your health care provider so that they can advise you on what is the best approach for your case after they do an examination on you and your condition.

Where to Purchase

Clindamycin Phosphate cannot be purchased over the counter. This is because of its highly medicated use and the adverse possible side effects. It is also because the drug is an antibiotic and by law, antibiotics should never be sold over the counter. For this reasons one can only get the gel after it has been prescribed to them by their health care providers.

Clindamycin Phosphate Topical Solution

This is an antibiotic topical solution used to treat acne vulgaris and should only be used on the skin. It is advisable to avoid contact with broken skin as absorption of the solution leads to serious side effects such as nausea, vomiting, stomach upset and diarrhea.

The side effects of using this solution are similar to those experienced when using the gel and the oral prescription. Some of them include; skin peeling, burning and itching of the skin and dry skin among others.

How to Use The Solution

The Clindamycin Phosphate solution is applied on the affected area using a swab known as the Clindamycin phosphate topical solution pledget. The medication is applied to the clean and dry affected area twice a day or as instructed by the doctor. Make sure you discard the swab after use and wash your hands thoroughly.

Notify your doctor if you are using other drugs because this it may interact with the drugs and will either inhibit their effectiveness or cause adverse side effects. Pregnant and breastfeeding women should also notify their doctors since certain amounts of the medicine are usually passed to the breast milk.


Nicotinamide is a vitamin found in food. It is a part of the vitamin B complex as it is rich in Vitamin B3 whose medical term is niacin.

It is normally used as a dietary supplement and as a medication.  When used as a supplement, it is administered as an oral drug and is present in a number of multivitamins usually containing about 20 to 30 mg of the vitamin in each supplement. This vitamin can be found in foods such as fish, meat nuts and mushrooms. It is normally effective in treating pellagra.

When it used as a medicine, nicotinamide is used to prevent skin aging and to treat skin acne. In the treatment of acne, it is usually in the form of a cream that prevents against inflammation and is beneficial to those people who have inflammatory skin conditions.

Nicotinamide is effective in improving the appearance of the skin, it enlarge skin pores, rejuvenating weakened skin surface and evening out uneven skin tone.

The side effects of this drug are usually very minimal and are safe to be used during pregnancy. When a high dose of nicotinamide is used, it normally causes liver problems.

Besides helping out with skin issues, niacin is beneficial with;

  • Balancing blood cholesterol levels hence maintaining a healthy cardiovascular system and metabolism.
  • Helps in brain function
  • Preventing and treating diabetes.

Some of the effects that have been reported among patients using medications with niacin include headaches, dizziness and low blood pressure, nausea and vomiting, some develop allergic reactions, aggravated gout symptoms and stomach or intestinal ulcers amongst others.

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